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Summary Objective: This review aims to demonstrate the conformal microwave ablation (MWA) of liver tumors might be attained by optimizing the composition of an aperiodic tri-slot coaxial antenna, its insertion depth, and enter power. Methods: A computational MWA product having an aperiodic tri-slot coaxial antenna running in the frequency of two.forty five GHz was created and validated by equally an ex vivo as well as a pilot in vivo experiment with porcine wholesome livers. The validated in vivo computational MWA design executed with a liver tumor was then utilized as a testbed to analyze the conformal ablation of liver tumors. Five liver tumors in various dimensions and designs had been investigated. A genetic algorithm optimization process (NSGA-II) was utilized to improve the composition of antenna, insertion depth of antenna, and microwave antenna input energy with the conformal ablation of liver tumors. Benefits: The validation final results confirmed that a fantastic agreement in both equally the spatiotemporal temperature distribution and ablation zone was identified between the computer design and also the ex vivo experiments at both equally 45 W, five min and sixty W, 3 min solutions as well as the in vivo experiment at forty five W, five min treatment.
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